A 68-year-old female patient presenting with peripheral arthralgia

Maria Douka, Nikolaos Kougkas, Apostolos H. Karantanas


A 68-year-old female patient presented to the Rheumatologic Outpatient Clinic with peripheral arthralgia of hands and feet for the last 3 months. Her past medical history included a thyroid cancer 25 years earlier.

Clinical examination revealed mild symmetrical polyarthritis with skin thickening and sclerosis of the upper extremities, more prominent on the right humerus (Fig. 1).

Laboratory work-up showed slightly elevated ESR and CRP and borderline blood eosinophilia. The complete blood count was normal and RF autoantibodies, anti-CCP and ANA were negative. She was referred for further evaluation with magnetic resonance (MR) imaging of the right upper limb (Figs. 2-4).


Eosinophilic fasciitis; Magnetic resonance imaging; Eosinophilia/diagnosis; Glucocorticoids/therapeutic use; Methotrexate/therapeutic use; Connective tissue diseases

Full Text:



Ihn H. Eosinophilic fasciitis: from pathophysiology to treatment. Allergol Int 2019; 68(4): 437-439.

Kirchgesner T, Dallaudière B, Omoumi P, et al. Eosinophilic fasciitis: typical abnormalities, variants and differential diagnosis of fasciae abnormalities using MR imaging. Diagn Interv Imaging 2015; 96: 341-348.

Fett N, Arthur M. Eosinophilic fasciitis: Current concepts of skin and systemic manifestations. Clin Dermatol 2018; 36(4): 487-497.

Pinal-Fernandez I, Selva-O' Callaghan A, Grau JM. Diagnosis and classification of eosinophilic fasciitis. Autoimm Rev 2014; 13: 379-382.

Chan V, Soans B, Mathers D. Ultrasound and magnetic resonance imaging features in a patient with eosinophilic fasciitis. Austral Radiol 2004; 48: 414-417.

Mazori DR, Femia AN, Vleugels RA. Eosinophilic fasciitis: an updated review on diagnosis and treatment. Curr Rheumatol Rep 2017; 19(12): 74.

Chatterjee S, Prayson R. Diffuse skin thickening, myalgias and joint stiffness in a 41-year-old man. CMAJ 2018; 190 (9): 258-261.

Moulton S, Kransdorf M, Ginsburg W, et al. Eosinophilic fasciitis: spectrum of MRI findings. AJR Am J Roentgenol 2005; 184: 975-978.

Baumann F, Brühlmann P, Andreisek G, et al. MRI for diagnosis and monitoring of patients with eosinophilic fasciitis. AJR Am J Roentgenol 2005; 184: 169-174.

Kim KT, Kim YJ, Lee JW, et al. Can necrotizing infectious fasciitis be differentiated from nonnecrotizing infectious fasciitis with MR imaging? Radiology 2011; 259(3): 816-824.

DOI: http://dx.doi.org/10.36162/hjr.v5i2.319


  • There are currently no refbacks.